- DNA patterns can unlock how glucose metabolism drives cancer, study finds
Less aggressive cancers are known to have an intact genome—the complete set of genes in a cell—while the genome of more aggressive cancers tends to have a great deal of abnormalities. Now, a new multi-year study of DNA patterns in tumor cells suggests that these aberrant genetic signatures are not random but reflect selective forces in tumor evolution.
February 15, 2017 9:00 AMdetail
- Scientists discover why some cancers may not respond to immunotherapy
UCLA scientists have discovered that people with cancers containing genetic mutations JAK1 or JAK2 will have little or no benefit from the immunotherapy drug, pembrolizumab.
February 06, 2017 3:00 AMdetail
- UCLA cancer research pioneer honored for advancing the understanding of treatment-resistant melanoma
The AACR will honor Dr. Roger Lo, an accomplished physician-scientist widely recognized his work in understanding treatment-resistant melanoma, with its first annual Waun Ki Hong Award for Outstanding Achievement in Cancer Research
January 30, 2017 10:00 AMdetail
- Combination therapy for glioblastoma shows promising results in early-stage research
UCLA researchers have discovered that combining a vaccine developed at UCLA with other experimental therapies and FDA-approved treatments shows promise for reducing the size of advanced brain tumors. The immunotherapy, which is specifically intended to treat brain tumors, is called autologous tumor lysate-pulsed dendritic cell vaccination. It uses a portion of the patient's own brain tumor and is currently being tested in humans.
January 23, 2017 6:00 AMdetail
- The unexpected intersection between art and science
It’s a common misconception that art and science are vastly different; that they never overlap. But creativity is as essential to the scientific process as it is to the artistic method. Artists and scientists share a curiosity for the unknown, an appreciation for the beauty of the worlds they explore and an interest in creating something new.
January 19, 2017 10:30 AMdetail
- With $3.2 million grant from NIH, UCLA researcher to optimize selection of lung cancer patients for immunotherapy
Dr. Edward Garon, UCLA Jonsson Comprehensive Cancer Center member and associate professor of hematology and oncology at the David Geffen School of Medicine, has received a five-year, $3.2 million grant from the National Institutes of Health to advance the understanding of which people with non-small cell lung cancer respond to immunotherapy.
January 17, 2017 9:30 AMdetail
- UCLA-led study provides roadmap to more personalized cancer treatment
Researchers have found that people with advanced head and neck squamous cell carcinoma and the KRAS-variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab in combination with standard chemotherapy and radiation.
December 22, 2016 8:00 AMdetail
- Chinese herbal treatment shows signs of effectiveness in bone marrow recovery
Researchers have found that a Chinese herbal regimen called TSY-1 (Tianshengyuan-1) TSY-1 increased telomerase activity in normal blood cells but decreased it in cancer cells. These results indicate that telomerase-based treatments may be of significance in treatments for both blood cell deficiency and cancer.
December 14, 2016 2:00 PMdetail
- ‘Turbocharged artificial intelligence’ could personalize combination therapy in pediatric leukemia
A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses.
December 12, 2016 9:00 AMdetail
- UCLA researchers uncover new evidence linking inflammation and increased prostate cancer risk
Results of a new UCLA study suggest that inflammation increases overall risk for prostate cancer by increasing the available pool of progenitor cells that can develop into the disease
December 06, 2016 9:00 AMdetail
- Genetic factors control regenerative properties of blood-forming stem cells, UCLA studies show
UCLA researchers have published two studies that define how key genetic factors affect blood-forming stem cells by either accelerating or hindering the cells’ regenerative properties. The findings could one day lead to improved treatments for people undergoing common therapies for cancer such as chemotherapy and radiation.
December 05, 2016 12:00 PMdetail